The game received positive reviews, being nominated to the Game Awards 2020, in the category Best Strategy/Tactics Games of 2020 The game has a vertical field, a train with 4 floors, with a pyre on the top floor. The enemies will try to reach the pyre to destroy it, and the player must protect it to achieve victory. Dan Stapleton, from IGN, wrote that the game is "a ticket to dozens – if not hundreds – of hours of challenging and surprising roguelike deckbuilding runs, thanks in large part to its mechanically diverse set of decks and the way they interact with each other when combined in different ways", and in his verdict, scored the game 9/10. Cody Peterson, from Screen Rant, wrote "Monster Train is an enjoyable deck building roguelike game that manages to reinvent both genres with some interesting new game mechanics", giving the game a 4 out of 5 star rating. Reviewing the Nintendo Switch version, titled Monster Train First Class, Waselenchuk of COGconnected praised the extensive amount of enemies and cards available; on the other hand, the author lamented the lack of touch screen functionality for the game: "I think many would agree; card games are often the ones that benefit the most from a touch screen". The game was nominated to the Game Awards 2020, in the category Best Strategy/Tactics Games of 2020.
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